Blood/Blood Cells and Cellular Components ›› Red Blood Cells ›› Abnormal


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Microscopic Features:
  • About the same size as a normal RBC
  • Slit-like or mouth-like central pallor (Hence the term stoma)
Normal % blood-PB, marrow-BM, lymphoid tissue-LN:
  • PB: Rare to None
  • BM: Rare to None
  • LN: Rare to None
May Resemble: Differential Diagnoses:

Increased in:
Hereditary stomatocytosis
Liver disease
Tangier disease
Rh null disease

Classic Immunophenotype:
  • N/A
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  • Similar to Hereditary Spherocytosis, Hereditary Stomatocytosis is also due to an underlying RBC membrane defect

Content Editors/Website Administrators:
Hooman H. Rashidi, MD; John C. Nguyen, MD