Blood/Blood Cells and Cellular Components ›› Red Blood Cells ›› Abnormal

Hemoglobin C Crystals*

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Microscopic Features:
  • Variable sized RBC crystalline dark blue-purple inclusions
  • Hexagon-shaped or rhomboid shaped crystalline structures in RBCs
Normal % blood-PB, marrow-BM, lymphoid tissue-LN:
  • PB: None
  • BM: None
  • LN: None
May Resemble: Differential Diagnoses:

Hemoglobin C disease
Hemoglobin SC disease

Classic Immunophenotype:
  • N/A
Cartoon Image:

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  • Hemoglobin C and SC patients may also show increased number of target cells

Content Editors/Website Administrators:
Hooman H. Rashidi, MD; John C. Nguyen, MD