Blood/Blood Cells and Cellular Components ›› Red Blood Cells ›› Abnormal

Hemoglobin C Crystals*


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› Microscopic Features:

• Variable sized RBC crystalline dark blue-purple inclusions
• Hexagon-shaped or rhomboid shaped crystalline structures in RBCs

› Normal % blood-PB, marrow-BM, lymphoid tissue-LN:

• PB: None
• BM: None
• LN: None

› May Resemble:

• Sickle cell [Compare]
• Bite cell [Compare]
• Target Cell [Compare]

› Differential Diagnoses:

Hemoglobin C disease Hemoglobin SC disease

› Classic Immunophenotype:

• N/A

› Cartoon Image:


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› Misc:

• Hemoglobin C and SC patients may also show increased number of target cells