Primary Hematopoietic and Lymphoid Tissue ›› Bone Marrow ›› Abnormal

Histoplasmosis in Histiocytes*

Click Here for Full Size

Microscopic Features:
  • Small round fungal forms seen within the cytoplasm of mature monocytes and histiocytes
Normal % blood-PB, marrow-BM, lymphoid tissue-LN:
  • PB: None
  • BM: None
  • LN: None
May Resemble:
  • Leishmania in Histiocytes [Compare]
  • Cellular debris in Histiocytes
  • Bacteria in Histiocytes
Differential Diagnoses:

Cellular debris within histiocytes
Bacterial infection

Classic Immunophenotype:
  • N/A
Cartoon Image:

Click and drag
for direct comparison

  • Histoplasma fungal forms lack kinetoplasts (small dark blue rod shaped structures within the organism) which are present in leishmania

Content Editors/Website Administrators:
Hooman H. Rashidi, MD; John C. Nguyen, MD