Primary Hematopoietic and Lymphoid Tissue ›› Bone Marrow ›› Abnormal

Mycobacteria in Histiocytes*

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Microscopic Features:
  • Rod shaped acid fast bacilli present in the cytoplasm of histiocytes
  • Acid fast stain highlights them as red rod shaped small structures
Normal % blood-PB, marrow-BM, lymphoid tissue-LN:
  • PB: None
  • BM: None
  • LN: None
May Resemble:
  • Histoplasma in histiocytes [Compare]
  • Leishmania in Histiocytes [Compare]
  • Cellular debris in Histiocytes
  • Bacteria in Histiocytes
Differential Diagnoses:

Cellular debris within histiocytes
Bacterial infection

Classic Immunophenotype:
  • N/A
Cartoon Image:

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  • Mycobacteria are usually Acid Fast Stain positive

Content Editors/Website Administrators:
Hooman H. Rashidi, MD; John C. Nguyen, MD