Primary Hematopoietic and Lymphoid Tissue ›› Bone Marrow ›› Abnormal

Mycobacteria in Histiocytes*


Click Here for Full Size

---

› Microscopic Features:

• Rod shaped acid fast bacilli present in the cytoplasm of histiocytes
• Acid fast stain highlights them as red rod shaped small structures

› Normal % blood-PB, marrow-BM, lymphoid tissue-LN:

• PB: None
• BM: None
• LN: None

› May Resemble:

• Histoplasma in histiocytes [Compare]
• Leishmania in Histiocytes [Compare]
• Cellular debris in Histiocytes
• Bacteria in Histiocytes

› Differential Diagnoses:

Leishmaniasis Histoplasmosis Cellular debris within histiocytes Bacterial infection

› Classic Immunophenotype:

• N/A

› Cartoon Image:


Click and drag

for direct comparison
› Misc:

• Mycobacteria are usually Acid Fast Stain positive