If in blood or increased numbers in bone marrow: Maybe increased in newborns (not to be confused with acute leukemia) May be seen in recovering bone marrows (e.g. post-treatment) Acute Leukemia
› Classic Immunophenotype:
› Cartoon Image:
Click and drag
for direct comparison
These are immature B-cells that are usually morphologically indistinguishable from lymphoblasts.
Hematogones are a immunophenotypically diverse group of immature B-cells (Earlier forms have less mature markers such as CD34 and TdT while the more mature forms lack CD34 and TdT and partially express CD20)
See the B-cell Maturation Diagram for more details