Blood/Blood Cells and Cellular Components ›› Red Blood Cells ›› Abnormal

Microcytic RBC: MCV <80*






Microscopic Features:
  • Slightly smaller than a normal mature RBC which correlates to the MCV of <80 fL
  • pallor is usually present (as opposed to a microspherocyte)
  • Can be hypochromic (central pallor greater than 1/3 of cell diameter)
Normal % blood-PB, marrow-BM, lymphoid tissue-LN:
  • PB: Rare to None
  • BM: Rare to None
  • LN: Rare to None
May Resemble:
  • Normal Mature RBC
  • Spherocyte
Differential Diagnoses:

Increased in:
Remember the Mnemonic "Puny TICS":
"Puny" for Pyridoxine deficiency
"T" for Thalassemia
"I" for Iron deficiency anemia
"C" for Chronic disease anemia (sometimes): AKA Anemia of Chronic Disease
"S" for Sideroblastic anemia (e.g. Lead poisoning): sometimes

Classic Immunophenotype:
  • N/A
Cartoon Image:



Misc:
  • Remember the Mnemonic "Puny TICS": "Puny" for Pyridoxine deficiency "T" for Thalassemia "I" for Iron deficiency anemia "C" for Chronic disease anemia (sometimes) "S" for Sideroblastic anemia (e.g. Lead poisoning): sometimes