Blood/Blood Cells and Cellular Components ›› Red Blood Cells ›› Abnormal

Hemoglobin C Crystals*

Microscopic Features:
  • Variable sized RBC crystalline dark blue-purple inclusions
  • Hexagon-shaped or rhomboid shaped crystalline structures in RBCs
Normal % blood-PB, marrow-BM, lymphoid tissue-LN:
  • PB: None
  • BM: None
  • LN: None
May Resemble:
  • Sickle cell
  • Bite cell
  • Target Cell
Differential Diagnoses:

Hemoglobin C disease
Hemoglobin SC disease

Classic Immunophenotype:
  • N/A
Cartoon Image:

  • Hemoglobin C and SC patients may also show increased number of target cells