HematologyOutlines - Atlas
Blood/Blood Cells and Cellular Components ›› Red Blood Cells ›› Abnormal

Hemoglobin C Crystals*


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› Microscopic Features:
  • Variable sized RBC crystalline dark blue-purple inclusions
  • Hexagon-shaped or rhomboid shaped crystalline structures in RBCs
› Normal % blood-PB, marrow-BM, lymphoid tissue-LN:
  • PB: None
  • BM: None
  • LN: None
› May Resemble:
  • Sickle cell
  • Bite cell
  • Target Cell
› Differential Diagnoses:

Hemoglobin C disease
Hemoglobin SC disease

› Classic Immunophenotype:
  • N/A
› Cartoon Image:



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RBC
for direct comparison

› Misc:
  • Hemoglobin C and SC patients may also show increased number of target cells