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Lymphoid >> Mature >> B-cell >> Non-Hodgkin Lymphoma

Mature B-cell Non-Hodgkin Lymphomas

-- Chronic lymphocytic leukemia/small lymphocytic lymphoma
-- B-cell prolymphocytic leukemia
-- Splenic marginal zone lymphoma
-- Hairy cell leukemia
-- Splenic B-cell lymphoma/leukemia, unclassifiable
---- Splenic diffuse red pulp small B-cell lymphoma
---- Hairy cell leukemia-variant
-- Lymphoplasmacytic lymphoma
-- Heavy chain diseases
---- Gamma heavy chain disease
---- Mu heavy chain disease
---- Alpha heavy chain disease
-- Plasma cell neoplasms
---- Monoclonal gammopathy of undetermined significance (MGUS)
---- Plasma cell myeloma
---- Solitary plasmacytoma of bone
---- Extraosseous plasmacytoma
---- Monoclonal immunoglobulin deposition diseases
-- Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT)
-- Nodal marginal zone lymphoma
-- Follicular lymphoma
-- Primary cutaneous follicle centre lymphoma
-- Mantle cell lymphoma
-- Diffuse large B-cell lymphoma, NOS
---- T cell/histiocyte-rich large B-cell lymphoma
---- Primary DLBCL of the CNS
---- Primary cutaneous DLBCL, leg type
---- EBV positive DLBCL of the elderly
-- DLBCL associated with chronic inflammation
-- Lymphomatoid granulomatosis
-- Primary mediastinal (thymic) large B-cell lymphoma
-- Intravascular large B-cell lymphoma
-- ALK Positive large B-cell lymphoma
-- Plasmablastic lymphoma
-- Large B-cell lymphoma arising in HHV8-assoc multicentric Castleman disease
-- Primary effusion lymphoma
-- Burkitt lymphoma

Lymphoid >> Mature >> T-cell >> T-cell/NK-cell Non-Hodgkin Lymphomas


Mature T-cell Non-Hodgkin Lymphomas and NK-cell Lymphoproliferative Diseases

CUTANEOUS
--Mycosis fungoides
--Primary cutaneous CD30+ T-cell lymphoproliferative disorders
----Cutaneous anaplastic large cell lymphoma
----Lymphomatoid Papulosis
--Subcutaneous panniculitis-like T-cell lymphoma
--Primary cutaneous peripheral T-cell lymphomas, rare subtypes

NODAL
--Peripheral T-cell lymphoma, NOS
--Angioimmunoblastic T-cell lymphoproliferative disorder
--Anaplastic large cell lymphoma (ALCL), ALK+
--Anaplastic large cell lymphoma (ALCL), ALK-

SYSTEMIC WITH LYMPHADENOPATHY
--T-cell prolymphocytic leukemia
--Aggressive NK-cell leukemia
--EBV+ T-cell lymphoproliferative disorders of childhood
--Adult T-cell leukemia/lymphoma
--Extranodal NK/T-cell lymphoma, nasal type
--Sézary syndrome

SYSTEMIC WITHOUT LYMPHADENOPATHY
--T-cell large granular lymphocytic leukemia
--Chronic lymphoproliferative disorders of NK-cells

OTHER/VISCERAL ORGANS
--Enteropathy-associated T-cell lymphoma (intestinal tract)
--Hepatosplenic T-cell lymphoma (liver and spleen)


Myeloid >> Immature >> Acute Myeloid Leukemia


Acute Myeloid Leukemia (AML)

--AML Myelodysplasia-related
--AML Therapy-Related
--AML Not Otherwise Specified (NOS)
----M0 (Minimally differentiated)
----M1 (Without Maturation)
----M2 (With Maturation)
----M4 (Myelomonocytic)
----M5 (Monocytic)
----M6 (Erythroid)
----M7 (Megakaryoblastic)
--AML with Recurrent Cytogenetics Abnormalities (Usually have better prognosis)
----t(15;17): Acute Promyelocytic Leukemia (M3) t(8;21) t(16;16) or Inv 16 etc.

Myeloid >> Mature/Maturing >> Myelodysplastic Syndromes


Myelodysplastic Syndrome (MDS)

--Refractory Anemia with Excess Blasts (RAEB)
----RAEB-I
----RAEB-II
--MDS with Multilineage Dysplasia
--MDS with Unilineage Dysplasia (e.g. Refractory Anemia)
--MDS-Unclassifiable
--MDS with isolated 5q del

Myeloid >> Mature/Maturing >> Myeloproliferative Neoplasms


Myeloproliferative Neoplasms (MPN)

--Chronic Myelogenous Leukemia (CML)
--Polycythemia Vera (PV)
--Essential Thrombocythemia (ET)
--Primary Myelofibrosis (PMF)
--Chronic Eosinophilic Leukemia
--Chronic Neutrophilic Leukemia

Myeloid >> Mature/Maturing >> Myelodysplastic/Myeloproliferative Neoplasms


Myelodysplastic/Myeloproliferative Neoplasms

--e.g. Chronic MyeloMonocytic Leukemia (CMML)

Lymphoid >> Mature >> B-cell >> Hodgkin Lymphomas


Hodgkin Lymphoma

--Classical Hodgkin Lymphoma (HL)
----Nodular Sclerosis HL
----Mixed Cellularity HL
----Lymphocyte Depleted HL
----Lymphocyte Rich HL
--Non-Classical Hodgkin Lymphoma
----Nodular Lymphocyte Predominant HL

Lymphoid >> Mature >> B-cell >> Plasma Cell Neoplasms


Plasma Cell Neoplasms

--Monoclonal Gammopathy of Undetermined Significance (MGUS)
--Plasma Cell Myeloma
--Solitary Plasmacytoma of Bone
--Extraosseus Plasmacytoma
--Monoclonal Immunoglobulin Deposition Diseases

Lymphoid >> Mature >> B-cell >> Immunodeficiency-Associated Lymphoproliferative Diseases


Immunodeficiency-Associated Lymphoproliferative Diseases

--Lymphoproliferative Diseases Associated with Primary Immune Disorders
--Lymphomas Associated with HIV Infection
--Post-transplant Lymphoproliferative Disorders (PTLD)

Lymphoid >> Immature >> B-cell


Immature B-cell Neoplasms

--B Lymphoblastic Leukemia/Lymphoma, NOS

Lymphoid >> Immature >> T-cell


Immature T-cell Neoplasms

--T Lymphoblastic Leukemia/Lymphoma, NOS

Other


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