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Bone Marrow: Erythroid (RBCs and Precursors)
Normal
►
Erythroid (RBC) Maturation Diagram
Normal
Pronormoblast*
Normal
Basophilic Normoblast*
Normal
Polychromatophilic Normoblast*
Normal
Orthochromic Normoblast*
Normal
Polychromatophilic RBC*
Normal
Normal mature RBC*
Abnormal
Ring Sideroblast*
Abnormal
Dysplastic Nucleated RBC*
Abnormal
Megaloblastoid Nucleated RBC*
Abnormal
Nucleated RBC with Parvovirus Infection*
Abnormal
Erythroid Leukemia (AML M6)*
Bone Marrow: Granulocytes and Precursors
Normal
►
Granulocytic Maturation Diagram
Normal
Myeloblast*
Normal
Promyelocyte*
Normal
Myelocyte*
Normal
Metamyelocyte*
Normal
Band*
Normal
Segmented Neutrophil*
Normal
Eosinophil (Precursor)*
Normal
Eosinophil (Mature)*
Normal
Basophil (Mature)*
Abnormal
Pseudo Pelger Huet Neutrophil*
Abnormal
Hypogranular or Agranular Neutrophil*
Abnormal
Myeloblast with Auer Rod*
Abnormal
Promyelocyte with Auer Rods*
Abnormal
Eosinophil (Increased)*
Abnormal
Dysplastic Eosinophil*
Abnormal
Basophils (increased)*
Bone Marrow: Neutrophilic
Normal
Myeloblast*
Normal
Promyelocyte*
Normal
Myelocyte*
Normal
Metamyelocyte*
Normal
Band*
Normal
Segmented Neutrophil*
Abnormal
Pseudo Pelger Huet Neutrophil*
Abnormal
Hypogranular or Agranular Neutrophil*
Abnormal
Myeloblast with Auer Rod*
Abnormal
Promyelocyte with Auer Rods*
Bone Marrow: Eosinophilic
Normal
Eosinophilic Precursor*
Normal
Eosinophil (Mature)*
Abnormal
Eosinophil (Increased)*
Abnormal
Dysplastic Eosinophil*
Bone Marrow: Basophilic
Normal
Basophil (Mature)*
Abnormal
Basophils (increased)*
Bone Marrow: Monocytes and Precursors
Normal
►
Monocyte Maturation Diagram
Normal
Monoblast*
Normal
Promonocyte*
Normal
Monocyte*
Abnormal
Increased Mature Monocytes*
Abnormal
Histoplasmosis in Histiocytes*
Abnormal
Leishmania in Histiocytes*
Abnormal
Mycobacteria in Histiocytes*
Bone Marrow: Megakaryocytes and Precursors
Normal
►
Megakarocyte Maturation Diagram
Normal
Megakaryocyte*
Normal
Platelets*
Abnormal
Micro-Megakaryocyte*
Abnormal
Dyslobated (Abnormal Lobation) Megakaryocyte*
Abnormal
Hypolobated Megakaryocytes (Increased)*
Abnormal
Staghorn-shaped Megakaryocyte*
Abnormal
Megakaryoblast (Increased)*
Bone Marrow: T-cells
Normal
►
T-cell Maturation Diagram
Normal
Immature T-cell precursor*
Normal
Mature T-cells*
Abnormal
T-Lymphoblasts (Increased)*
Abnormal
Large Granular Lymphocyte (LGL)*
Abnormal
Increased Mature T-cells*
Bone Marrow: B-cells
Normal
►
B-cell Maturation Diagram
Normal
Immature B-cell (Early Hematogone)*
Normal
Immature B-cell (Later Hematogone)*
Normal
Mature B-cells
Abnormal
Increased B-Lymphoblasts
Abnormal
Increased Mature appearing B-cells
Bone Marrow: Plasma Cells
Normal
Plasma Cell*
Abnormal
Plasma Cell Myeloma (AKA Multiple Myeloma)*
Abnormal
Plasmablast (Immature plasma cell)*
Bone Marrow: NK Cells
Normal
NK Cell*
Thymus
Normal
►
T-cell Maturation in Thymus (Diagram)
Abnormal
T-cell Lymphoblastic Leukemia/Lymphoma (T-ALL)*
Lymph Node
Normal
►
Normal Lymph Node Diagram
Normal
►
B-cell Maturation in Lymph Node Diagram
Normal
Normal Lymph Node*
Non-neoplastic
Lymphadenitis (Non-neoplastic)*
Neoplastic: Hodgkin Lymphoma
Classical Hodgkin Lymphoma*
Neoplastic: Non-Hodgkin Lymphoma
Follicular Lymphoma*
Neoplastic: Non-Hodgkin Lymphoma
Small Lymphocytic Lymphoma*
Neoplastic: Non-Hodgkin Lymphoma
Diffuse Large B-cell Lymphoma*
Neoplastic: Non-Hodgkin Lymphoma
Mantle Cell Lymphoma*
Neoplastic: Non-Hodgkin Lymphoma
Burkitt Lymphoma*
Neoplastic: Non-Hodgkin Lymphoma
T-cell Lymphoma: ALK+ Anaplastic Large Cell Lymphoma*
Mucosa-Associated Lymphoid Tissue (MALT)
Normal
GI Tract (Non-Gastric, e.g. Small Bowel): Mucosa Associated Lymphoid Tissue (MALT)*
Abnormal
MALT Lymphoma (e.g. Gastric)*
Spleen
Normal
Normal Spleen*
Normal
►
B-cell Maturation in Spleen Diagram
Abnormal
Hairy Cell Leukemia*
Abnormal
Splenic Marginal Zone Lymphoma*
Peripheral Blood: Red Blood Cells
Normal
►
Erythrocyte (RBC) Maturation Diagram
Normal
Normal mature RBC*
Normal
Polychromatophilic RBC*
Abnormal
►
Diagram of Abnormal Red blood Cell Morphologies in blood
Abnormal
Microcytic RBC: MCV <80*
Abnormal
Macrocytic RBC: MCV >100*
Abnormal
Spur cell RBC (Acanthocyte)*
Abnormal
Burr cell RBC (Echinocyte)*
Abnormal
Schistocyte: Fragmented RBC*
Abnormal
Bite Cell RBC*
Abnormal
Elliptocyte (Ovalocyte)*
Abnormal
Spherocyte*
Abnormal
Stomatocyte*
Abnormal
Target Cell RBC*
Abnormal
Sickle Cell*
Abnormal
Teardrop Cell*
Abnormal
Hemoglobin C Crystals*
Abnormal
Red Cell Agglutinate*
Abnormal
Rouleaux*
Abnormal
►
Diagram of Red blood Cell Inclusions
Abnormal
Howell Jolly Bodies*
Abnormal
Heinz Bodies*
Abnormal
Pappenheimer Bodies*
Abnormal
Hemoglobin H Inclusion*
Abnormal
Basophilic Stippling*
Abnormal
►
Diagram of Infections involving the peripheral blood
Abnormal
Infectious-Malaria*
Abnormal
Infectious-Babesia*
Abnormal
Infectious-Trypanosoma*
Abnormal
Infectious-Microfilaria*
Abnormal
Bacterial contamination in peripheral blood smear*
Abnormal
Infectious-Borrelia*
Abnormal
Infectious-Fungus (Candida)*
Peripheral Blood: Neutrophils
Normal
►
Granulocytic Maturation Diagram
Normal
Band Neutrophil*
Normal
Segmented Neutrophil*
Abnormal
Myeloblast*
Abnormal
Promyelocyte*
Abnormal
Myelocyte*
Abnormal
Metamyelocyte*
Abnormal
May Hegglin Anomaly*
Abnormal
Hypersegmented Neutrophil*
Abnormal
Neutrophil with toxic granules*
Abnormal
Pseudo Pelger Huet Neutrophil*
Abnormal
Hypogranular or Agranular Neutrophil*
Abnormal
Chediak Higashi Neutrophils*
Peripheral Blood: Eosinophils and Basophils
Normal
Eosinophil (Mature)*
Abnormal
Eosinophil (Increased)*
Abnormal
Dysplastic Eosinophil*
Normal
Basophil (Mature)*
Abnormal
Basophils (increased)*
Peripheral Blood: Monocytes
Normal
►
Monocyte Maturation Diagram
Normal
Monocyte*
Abnormal
Monoblast*
Abnormal
Promonocyte*
Abnormal
Increased Mature Monocytes*
Peripheral Blood: Lymphocytes
Normal B-cell Maturation
►
B-cell Maturation Diagram
Normal T-cell Maturation
►
T-cell Maturation Diagram
Normal B-cell Maturation
►
B-cell Maturation in Lymph Node Diagram
Normal T-cell Maturation
►
T-cell Maturation in Thymus Diagram
Normal
Lymphocyte-Normal*
Abnormal
Lymphocyte-Abnormal*
Abnormal
Reactive Lymphocyte*
Abnormal
Large Granular Lymphocyte (LGL)*
Abnormal
Chronic Lymphocytic Leukemia (CLL)*
Abnormal
Lymphoblasts (e.g. Acute Lymphoblastic Leukemia: ALL)*
Abnormal
Hairy Cell Leukemia*
Abnormal
Sezary Cell*
Peripheral Blood: Platelets
Normal
Platelets*
Abnormal
Platelet Satellitosis*
Abnormal
Giant Platelets*
Abnormal
Agranular Platelets*
Test your knowledge:
Peripheral Blood Smear
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Multiple Choice Quiz (Bone Marrow Components)
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Multiple Choice Quiz (Peripheral Blood Components)
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Glossary Matching - All Terms
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Content Editors/Website Administrators:
Hooman H. Rashidi, MD; John C. Nguyen, MD