Primary Hematopoietic and Lymphoid Tissue ›› Bone Marrow ›› Abnormal

Dysplastic Eosinophil*

Click Here for Full Size

Additional Image 1 Additional Image 2

Microscopic Features:
  • 2-3x larger than a mature RBC
  • Low nuclear to cytoplasmic (N/C) ratio (more cytoplasm than nucleus)
  • Nucleus is mature and usually with 2 lobes connected by thin chromatin filament (some have 1 lobe or more than 2 lobes)
  • Nucleoli are usually absent
  • More cytoplasm with Abnormal secondary granules (usually darker in color resembling basophilic granules). The granules are usually heterogenous and sometimes vacuoles may also be noted.
Normal % blood-PB, marrow-BM, lymphoid tissue-LN:
  • PB: None
  • BM: None
  • LN: None
May Resemble: Differential Diagnoses:

Associated with:
Certain AMLs such as AML with Inv 16 or t(16;16)
Certain Myeloid disorders/neoplasms
Artifact of staining must be ruled out

Classic Immunophenotype:
  • N/A
Cartoon Image:

Click and drag
for direct comparison

  • May be associated with certain myeloid neoplasms such as AML with invresion 16 or t(16;16)

Content Editors/Website Administrators:
Hooman H. Rashidi, MD; John C. Nguyen, MD