Acute phase response

Is also known as acute phase reaction and is an inflammatory response to injury which may be related to an underlying infection, trauma, ischemia, immunologic or neoplastic process. During this reaction, the liver produces "acute phase proteins" which include but are not limited to CRP, fibrinogen, Factor VIII, Ferritin, Hepcidin, Ceruloplasmin and haptoglobin. Hence, evaluating the levels of these proteins in the setting of inflammation may be problematic.