Anti-c

Antibody formed against one of the antigens that comprise part of the RhCE protein. Because of genetic linkage, anti-c is frequently found along with anti-E. The c antigen belongs to the Rh antigen system. Anti-c antibodies are usually formed in response to transfusion or pregnancy. Anti-c antibodies are clinically significant and can cause acute or delayed hemolytic transfusion reactions or hemolytic disease of the fetus and newborn (HDFN) if the patient is challenged with antigen positive blood.