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Blood/Blood Cells and Cellular Components ›› Red Blood Cells ›› Abnormal

Bacterial contamination in peripheral blood smear

Bacterial contamination in peripheral blood smear
Bacterial contamination in peripheral blood smear
Bacterial contamination in peripheral blood smear

Microscopic Features:

  • Bacterial colonies (usually cocci in chains and clusters) over RBCs
  • The contaminating bacteria are usually cocci (dark blue round structures much smaller than the RBC)

Normal % blood-PB, marrow-BM, lymphoid tissue-LN:

  • PB: None
  • BM: None
  • LN: None

May Resemble:

  • Platelets overlying red blood cell
  • Artifacts (e.g. Stain precipitate)
  • Real Bacterial infection

Differential Diagnoses:

Artifact
Real bacterial infection involving blood

Classic Immunophenotype:

  • N/A

Cartoon Image:

Bacterial contamination in peripheral blood smear cartoon
Click and dragRed blood cell for scalefor direct comparison

Misc:

Bacterial colonies (usually cocci: most likely Staphlococcus epidermidis) from contaminated handling during processing of the peripheral blood smear by the medical technologist