Aspirin

a.k.a. Acetylsalicylic acid belongs to the non-steroid anti-inflammatory drug (NSAID) family which is used as an analgesic, antipyretic, and anti-inflammatory agent. Because of its anti-platelet properties, it is used in low dosage to prevent myocardial infarction, stroke, and thrombus formation. Main mechanism of actions includes irreversible binding of cyclooxygenase-1 (COX-1) and modification of Cox-2, thus decreases the production of prostaglandin and thromboxane A2. Hence, irreversibly effects the function of the platelets and may be problematic if the patient is on Aspirin and planned for a surgical procedure. Additionally, usage in children or adolescents for fever or other illnesses can cause Reye’s syndrome.