CD20

A type of CD which is normally expressed in most mature B-cells. It is usually negative in early hematogones and normal plasma cells. Recall the CD_Mnemonic, "B" for "B-cells" & "Bigger" CDs (CD19, 20, 21, 22, 23, 24) which are typicaly expressed in "B-cells". Most mature B-cell lymphoma/leukemias are CD20 positive. CD20 is typically negative in most plasma cell neoplasms (e.g. Plasma cell Myeloma). CD20 expression on lymphomas is also very important clinically since there is an Anti-CD20 drug (Rituximab) that is typically used as part of the treatment of these lymphomas.