H. H. Rashidi, MD
J. C. Nguyen, MD
HematologyOutlines.com

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Hypersegmented neutrophils

These are neutrophils with more than 5 lobes (so 6 or more lobes. Recall, normal neutrophils should have 3-5 lobes). Hypersegmented neutrophils are most commonly associated with B12 or Folate deficiency (two common causes of a Macrocytic Anemia).
Atlas Link: Hypersegmented Neutrophil
Hypersegmented neutrophils – Figure 1
Hypersegmented neutrophils – Figure 1
Figure 1 · click to enlarge
Hypersegmented neutrophils – Figure 2
Hypersegmented neutrophils – Figure 2
Figure 2 · click to enlarge
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