MDS with isolated 5q-

Also known as MDS with isolated 5q deletion is a type of MDS characteristically showing normal or elevated platelet count with a bone marrow displaying increased numbers of hypolobated megakaryocytic along with erythroid hypoplasia. The normal or increased platelet count is unusual amongst MDS, and when the 5q- is the sole cytogenetic abnormality, the prognosis is better than most MDS. These patients are usually treated with lenalidomide.