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Blood/Blood Cells and Cellular Components ›› Red Blood Cells ›› Abnormal

Burr cell RBC (Echinocyte)

Burr cell RBC (Echinocyte)
Burr cell RBC (Echinocyte)
Burr cell RBC (Echinocyte)
Additional Image 1: Burr cell RBC (Echinocyte)
Additional image 1: Burr cell RBC (Echinocyte)
Additional Image 2: Burr cell RBC (Echinocyte)
Additional image 2: Burr cell RBC (Echinocyte)

Microscopic Features:

  • May be smaller or the size as a normal RBC
  • Regular broader-base short blunt projections of red cell membrane

Normal % blood-PB, marrow-BM, lymphoid tissue-LN:

  • PB: Rare to None
  • BM: Rare to None
  • LN: Rare to None

May Resemble:

Differential Diagnoses:

Increased in:
Artifact (e.g. older blood specimen)
Uremia (e.g. chronic renal disease)
Liver disease
Hyperlipidemia
Etc.

Classic Immunophenotype:

  • N/A

Cartoon Image:

Burr cell RBC (Echinocyte) cartoon
Click and dragRed blood cell for scalefor direct comparison

Misc:

Most often they are due to an artifact of smear preparation. Also one must inquire about the age of the blood sample.