JAK2

Also known as Janus Kinase 2 is a protein whose signaling is involved in many receptor families including but not limited to Erythropoietin and Thrombopoietin Receptors. Mutation of JAK2 has been identified in many myeloproliferative neoplasms such as Polycythemia Vera, Essential Thrombocythemia and Primary Myelofibrosis.