H. H. Rashidi, MD
J. C. Nguyen, MD
HematologyOutlines.com

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Blood/Blood Cells and Cellular Components ›› Lymphocytes ›› Abnormal

Lymphocyte-Abnormal

Lymphocyte-Abnormal
Lymphocyte-Abnormal
Lymphocyte-Abnormal

›Microscopic Features:

  • Range in size from slightly (1.5x) larger than a mature RBC to 2-4x larger than a RBC
  • High nuclear to cytoplasmic ratio but with
  • Round mature Nucleus (clumped chromatin)
  • Nucleoli are absent in most
  • Cytoplasm is scant, light blue and lacks granules

›Normal % blood-PB, marrow-BM, lymphoid tissue-LN:

  • PB: None
  • BM: None
  • LN: None

›May Resemble:

›Differential Diagnoses:

If increased in blood, Lymph node or bone marrow:
Infection
Neoplastic (mature B or T-cell lymphoma or leukemia)

›Classic Immunophenotype:

  • N/A

›Cartoon Image:

Lymphocyte-Abnormal cartoon
Click and dragRed blood cell for scalefor direct comparison

›Misc:

It is not possible to distinguish T-cells and B-cells based on morphology alone.